ncRNA name | hsa-miR-34a |
ncRNA Category | miRNA |
Disease name | uveal melanoma (UM) |
Species | Homo sapiens |
Tissues/Cell_line | human UM cell lines M17, M21, M23 and SP6.5; human melanocyte cell line D78; human embryonic kidney cell line HEK293; human UM specimens |
Methods | Northern blot, MTS cell proliferation, transwell assay, luciferase reporter assay, immunofluorescence staining, Western blot |
Expression pattern | down-regulated |
Functional description | miR-34a acts as a tumor suppressor in uveal melanoma cell proliferation and migration through the downregulation of c-Met. |
PubMed ID | 19029026 |
Year | 2009 |
Title | MicroRNA-34a inhibits uveal melanoma cell proliferation and migration through downregulation of c-Met. |
Drug-related ncRNA | NO |
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